Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.65 |
| ▸ | KDM5A | P29375 | 7/20 | 0.49 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.49 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095206 | 0.91 | KDM4C (0.64) | KDM4CKDM5AKDM5BKMOKDM2B | |
| SCHEMBL16033531 | 0.79 | KDM4C (1.00) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL20978720 | 0.77 | KDM4C (0.69) | KDM4CKDM5AKDM5BKMOSLC6A2 | |
| SCHEMBL16095331 | 0.72 | KDM2B (0.55) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL16095431 | 0.72 | KDM5B (0.41) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL16095345 | 0.72 | KDM4C (0.44) | KDM4CKDM5AKDM5BKMOKDM4A | |
| SCHEMBL16095088 | 0.72 | KDM5B (0.44) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL16095045 | 0.71 | KDM5B (0.48) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL16095741 | 0.70 | KDM4C (0.60) | KDM4CKDM5AKDM5BKMOKDM4A | |
| SCHEMBL16095275 | 0.70 | KDM4C (0.49) | KDM4CKDM5AKDM5BKDM2BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014151945-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |