Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 12/20 | 0.69 |
| ▸ | KDM5A | P29375 | 7/20 | 0.52 |
| ▸ | KDM5B | Q9UGL1 | 7/20 | 0.52 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20978862 | 0.91 | KDM4C (0.68) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL16033531 | 0.81 | KDM4C (1.00) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL20978805 | 0.77 | KDM5B (0.59) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL16095915 | 0.77 | KDM4C (0.65) | KDM4CKDM5AKDM5BKMOKDM2B | |
| SCHEMBL20978783 | 0.74 | KDM2B (0.64) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL20978718 | 0.73 | KDM4C (0.63) | KDM4CKDM5AKDM5BKMOKDM2B | |
| SCHEMBL16033693 | 0.72 | KDM4C (1.00) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL20978815 | 0.72 | KDM4C (0.48) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL20978910 | 0.72 | KDM5A (0.60) | KDM4CKDM5AKDM5BKDM2BKDM4A | |
| SCHEMBL20978807 | 0.70 | KDM5B (0.62) | KDM4CKDM5AKDM5BKDM2BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969007-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2019-05-08 | — | — | EP | disclosed |