Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16095987 | 1.00 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNAHSD17B10NOS3 | |
| SCHEMBL17499171 | 0.86 | RAB9A (0.35) | ALDH1A1MAPTLMNAHSD17B10NOS3 | |
| SCHEMBL17499689 | 0.85 | NPC1 (0.34) | ALDH1A1MAPTLMNAHSD17B10NOS3 | |
| SCHEMBL16096772 | 0.76 | GRIN2B (0.43) | MAPTLMNAHSD17B10GRIN1GRIN2B | |
| SCHEMBL16096771 | 0.76 | GRIN2B (0.43) | MAPTLMNAHSD17B10GRIN1GRIN2B | |
| SCHEMBL16096204 | 0.75 | GAA (0.50) | ALDH1A1MAPTLMNAHSD17B10NOS3 | |
| SCHEMBL16096205 | 0.75 | GAA (0.50) | ALDH1A1MAPTLMNAHSD17B10NOS3 | |
| SCHEMBL16095897 | 0.75 | MAPT (0.48) | ALDH1A1MAPTLMNAHSD17B10NOS3 | |
| SCHEMBL16102246 | 0.74 | RAB9A (0.55) | ALDH1A1MAPTLMNAHSD17B10NOS3 | |
| SCHEMBL15137199 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAHSD17B10NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | Bridgestone Corporation (JP) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014149931-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORPORATION (JP) | 2014-09-25 | — | — | WO | disclosed |