Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1609694 | 0.87 | SMN1; SMN2 (0.41) | KMT2AKDM4EMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12713240 | 0.85 | CHRM3 (0.39) | HTTKDM4EALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL1609555 | 0.83 | ALDH1A1 (0.36) | KMT2AHTTKDM4EMEN1ALDH1A1 | |
| SCHEMBL1609575 | 0.83 | CRHBP (0.40) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1609907 | 0.82 | ALDH1A1 (0.41) | KMT2AHTTKDM4EMEN1ALDH1A1 | |
| SCHEMBL1609556 | 0.81 | KDM4E (0.43) | KMT2AHTTKDM4EMEN1ALDH1A1 | |
| SCHEMBL1610224 | 0.80 | SLC6A3 (0.40) | KMT2AKDM4EMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1609979 | 0.79 | PDE4B (0.42) | HTTKDM4EALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL1609421 | 0.78 | PDE10A (0.43) | KMT2AKDM4EMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1609728 | 0.78 | PDE10A (0.42) | KMT2AKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| WO-2009081112-A2 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | KMT2A 2003/4885HTT 1789/4885KDM4E 2613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.