Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 2/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16097397 | 0.88 | SCN8A (0.32) | SCN8ANOTUMLMNA | |
| SCHEMBL17499680 | 0.86 | SCN8A (0.32) | SCN8ANOTUMLMNA | |
| SCHEMBL16097907 | 0.84 | SCN8A (0.44) | TRPM5SCN8AL3MBTL1KDM4ESYK | |
| SCHEMBL16095208 | 0.82 | KDM4E (0.40) | LMNAL3MBTL1KDM4ESYKKMT2A | |
| SCHEMBL16098341 | 0.81 | SYK (0.37) | TRPM5NOTUMLMNAL3MBTL1KDM4E | |
| SCHEMBL16096168 | 0.80 | ALDH1A1 (0.36) | SCN8ALMNAL3MBTL1KDM4EKMT2A | |
| SCHEMBL16095252 | 0.77 | CTH (0.35) | SCN8ANOTUMLMNAL3MBTL1KDM4E | |
| SCHEMBL16095251 | 0.77 | CTH (0.35) | SCN8ANOTUMLMNAL3MBTL1KDM4E | |
| SCHEMBL16098400 | 0.76 | KDM4E (0.40) | L3MBTL1KDM4ESYKKMT2AMEN1 | |
| SCHEMBL16095541 | 0.76 | KDM4E (0.43) | LMNAKDM4ESYKKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |
| EP-2969593-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | Bridgestone Corporation (JP) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014149931-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORPORATION (JP) | 2014-09-25 | — | — | WO | disclosed |