Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 13/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.30 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.30 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16097340 | 1.00 | POLB (0.40) | POLBTDP1KMT2ANPC1RAB9A | |
| SCHEMBL16095843 | 0.88 | POLB (0.42) | POLBTDP1KMT2ANPC1RAB9A | |
| SCHEMBL16095841 | 0.88 | POLB (0.42) | POLBTDP1KMT2ANPC1RAB9A | |
| SCHEMBL17499423 | 0.84 | POLB (0.40) | POLBTDP1KMT2ANPC1RAB9A | |
| SCHEMBL16102676 | 0.81 | LMNA (0.35) | NPC1RAB9AGAA | |
| SCHEMBL17499249 | 0.81 | LMNA (0.35) | NPC1RAB9AGAA | |
| SCHEMBL17499137 | 0.80 | — | — | |
| SCHEMBL16096707 | 0.80 | — | — | |
| SCHEMBL17499623 | 0.78 | LMNA (0.34) | TDP1KMT2ANPC1RAB9AGAA | |
| SCHEMBL16101947 | 0.78 | ALDH1A1 (0.43) | POLBKMT2ANPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |
| EP-2969593-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | Bridgestone Corporation (JP) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014149931-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORPORATION (JP) | 2014-09-25 | — | — | WO | disclosed |