Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16096772 | 0.86 | GRIN2B (0.43) | NPC1RAB9AGRIN1GRIN2BSMN1; SMN2 | |
| SCHEMBL16096771 | 0.86 | GRIN2B (0.43) | NPC1RAB9AGRIN1GRIN2BSMN1; SMN2 | |
| SCHEMBL17499724 | 0.84 | NPC1 (0.33) | NPC1RAB9AGRIN1GRIN2BSMN1; SMN2 | |
| SCHEMBL16096649 | 0.79 | IDO1 (0.33) | NPC1RAB9AGRIN1GRIN2BSMN1; SMN2 | |
| SCHEMBL17499694 | 0.79 | GRIN2B (0.33) | GRIN1GRIN2BHTR7 | |
| SCHEMBL17499689 | 0.78 | NPC1 (0.34) | NPC1RAB9ASMN1; SMN2ALOX15CDK2 | |
| SCHEMBL17499397 | 0.77 | GRIN1 (0.32) | NPC1RAB9AGRIN1GRIN2BHTR7 | |
| SCHEMBL17499826 | 0.76 | GRIN1 (0.32) | GRIN1GRIN2BHTR7 | |
| SCHEMBL16096615 | 0.75 | GRIN1 (0.32) | GRIN1GRIN2BHTR7 | |
| SCHEMBL17499700 | 0.73 | GRIN1 (0.33) | GRIN1GRIN2BHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |
| EP-2969593-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | Bridgestone Corporation (JP) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014149931-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORPORATION (JP) | 2014-09-25 | — | — | WO | disclosed |