Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CLK2 | P49760 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499765 | 0.86 | GRIN2B (0.42) | GRIN1GRIN2BCLK2GSK3AGSK3B | |
| SCHEMBL16098425 | 0.84 | GLA (0.32) | GRIN1GRIN2BHTR7KMT2ANPC1 | |
| SCHEMBL16098426 | 0.84 | GLA (0.32) | GRIN1GRIN2BHTR7KMT2ANPC1 | |
| SCHEMBL17499620 | 0.79 | KMT2A (0.33) | KMT2ANPC1RAB9A | |
| SCHEMBL17499826 | 0.78 | GRIN1 (0.32) | GRIN1GRIN2BHTR7 | |
| SCHEMBL16097693 | 0.77 | NPC1 (0.32) | GRIN1GRIN2BHTR7NPC1RAB9A | |
| SCHEMBL16096615 | 0.77 | GRIN1 (0.32) | GRIN1GRIN2BHTR7 | |
| SCHEMBL16096649 | 0.76 | IDO1 (0.33) | GRIN1GRIN2BNPC1RAB9A | |
| SCHEMBL17499694 | 0.75 | GRIN2B (0.33) | GRIN1GRIN2BHTR7 | |
| SCHEMBL17499700 | 0.75 | GRIN1 (0.33) | GRIN1GRIN2BHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |