Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16096810 | 0.86 | ALDH1A1 (0.38) | ALDH1A1CYP1A2CYP3A4HPGDCYP2C19 | |
| SCHEMBL16098415 | 0.83 | ALDH1A1 (0.36) | ALDH1A1CYP1A2CYP3A4HPGDCYP2C19 | |
| SCHEMBL17499112 | 0.81 | HPGD (0.33) | ALDH1A1CYP1A2CYP3A4HPGDCYP2C19 | |
| SCHEMBL16096136 | 0.81 | HPGD (0.36) | ALDH1A1CYP1A2CYP3A4HPGDCYP2C19 | |
| SCHEMBL16096761 | 0.78 | SCN4A (0.33) | ALDH1A1CYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL16098116 | 0.78 | LMNA (0.37) | ALDH1A1CYP1A2HPGDCYP2C19HSD17B10 | |
| SCHEMBL16096279 | 0.77 | LMNA (0.39) | ALDH1A1CYP1A2HPGDCYP2C19KMT2A | |
| SCHEMBL16097527 | 0.77 | MAPT (0.56) | ALDH1A1CYP1A2CYP3A4HPGDCYP2C19 | |
| SCHEMBL16097525 | 0.77 | MAPT (0.56) | ALDH1A1CYP1A2CYP3A4HPGDCYP2C19 | |
| SCHEMBL16096533 | 0.76 | POLB (0.35) | ALDH1A1CYP1A2CYP3A4HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |
| EP-2969593-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | Bridgestone Corporation (JP) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014149931-A1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORPORATION (JP) | 2014-09-25 | — | — | WO | disclosed |