Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 5/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1609605 | 0.87 | PDE10A (0.44) | GAATHRBPDE10AALOX5HSP90AA1 | |
| SCHEMBL1609787 | 0.86 | GAA (0.37) | GAATHRBPDE10ASMN1; SMN2ALOX5 | |
| SCHEMBL12712921 | 0.82 | CHRM3 (0.40) | PDE10ASMN1; SMN2POLBKMT2ALMNA | |
| SCHEMBL1610061 | 0.77 | PDE10A (0.43) | PDE10ASMN1; SMN2LMNA | |
| SCHEMBL1609886 | 0.74 | CHRM3 (0.38) | PDE10ASMN1; SMN2POLBKMT2ALMNA | |
| SCHEMBL1613175 | 0.73 | TUBB4A (0.41) | PDE10APOLBKMT2A | |
| SCHEMBL1609799 | 0.73 | NFE2L2 (0.37) | SMN1; SMN2KMT2ALMNA | |
| SCHEMBL1609798 | 0.73 | NFE2L2 (0.37) | SMN1; SMN2KMT2ALMNA | |
| SCHEMBL1609450 | 0.72 | TUBB4A (0.42) | GAAPDE10ASMN1; SMN2POLBTP53 | |
| SCHEMBL1609421 | 0.72 | PDE10A (0.43) | GAAPDE10ASMN1; SMN2HSP90AA1HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | GAA 1293/4885THRB 1495/4885PDE10A 1704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.