Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.31 |
| ▸ | BRD7 | Q9NPI1 | 3/20 | 0.31 |
| ▸ | TAF1 | P21675 | 2/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.31 |
| ▸ | CECR2 | Q9BXF3 | 2/20 | 0.31 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.31 |
| ▸ | BPTF | Q12830 | 1/20 | 0.31 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.31 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.31 |
| ▸ | ATAD2B | Q9ULI0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16099109 | 0.89 | PDE2A (0.33) | DYRK1AMAOAHASPINAAK1PDE2A | |
| SCHEMBL16099606 | 0.80 | IDO1 (0.34) | DYRK1AMAOAHASPINPDE2AROCK2 | |
| SCHEMBL21384189 | 0.78 | HASPIN (0.32) | DYRK1AMAOAHASPIN | |
| SCHEMBL16098607 | 0.77 | HASPIN (0.41) | DYRK1AMAOAHASPINAAK1PDE2A | |
| SCHEMBL16099516 | 0.76 | HASPIN (0.47) | DYRK1AMAOAHASPINNFATC1GSK3B | |
| SCHEMBL16097799 | 0.69 | ADORA3 (0.33) | KAT2BROCK2PLK1 | |
| SCHEMBL16093837 | 0.68 | HASPIN (0.49) | DYRK1AMAOAHASPINCYP2D6ROCK2 | |
| SCHEMBL16099755 | 0.66 | HASPIN (0.44) | DYRK1AMAOAHASPINNFATC1GSK3B | |
| SCHEMBL16099711 | 0.65 | HASPIN (0.43) | DYRK1AMAOAHASPINCYP2D6ROCK2 | |
| SCHEMBL30939967 | 0.64 | DYRK1A (0.62) | DYRK1AMAOAHASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968284-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | Osteoqc Inc. (CA) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014153203-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSSIFI INC. (US) | 2014-09-25 | — | — | WO | disclosed |