Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.31 |
| ▸ | CDK4 | P11802 | 2/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16098616 | 0.90 | ADORA3 (0.32) | ADORA3ADORA2ATRPV1 | |
| SCHEMBL16097995 | 0.78 | CYP2D6 (0.38) | ADORA3ADORA2ASCN9AROCK2 | |
| SCHEMBL16099656 | 0.74 | ADORA3 (0.39) | ADORA3ADORA2A | |
| SCHEMBL16099365 | 0.71 | CYP2D6 (0.35) | ADORA3ADORA2AROCK2 | |
| SCHEMBL16098288 | 0.69 | DYRK1A (0.34) | KAT2BROCK2PLK1 | |
| SCHEMBL16099686 | 0.67 | NFATC1 (0.41) | — | |
| SCHEMBL16123503 | 0.67 | HASPIN (0.39) | PLK1 | |
| SCHEMBL30939978 | 0.67 | HASPIN (0.39) | PLK1 | |
| SCHEMBL16099839 | 0.65 | HASPIN (0.39) | ROCK2MAPT | |
| SCHEMBL16099097 | 0.64 | HASPIN (0.45) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968284-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | Osteoqc Inc. (CA) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014153203-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSSIFI INC. (US) | 2014-09-25 | — | — | WO | disclosed |