Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16098749 | 0.88 | TSHR (0.33) | TSHRZDHHC20ZDHHC2 | |
| SCHEMBL16776767 | 0.85 | ZDHHC20 (0.42) | TSHRZDHHC20ZDHHC2 | |
| SCHEMBL14341773 | 0.85 | ZDHHC20 (0.38) | TSHRZDHHC20ZDHHC2 | |
| SCHEMBL2455781 | 0.83 | ZDHHC20 (0.44) | TSHRZDHHC20ZDHHC2 | |
| SCHEMBL16776749 | 0.83 | ZDHHC20 (0.44) | TSHRZDHHC20ZDHHC2 | |
| SCHEMBL3255350 | 0.80 | ALDH1A1 (0.38) | TSHRZDHHC20ZDHHC2 | |
| SCHEMBL325417 | 0.79 | ZDHHC20 (0.46) | TSHRZDHHC20ZDHHC2 | |
| SCHEMBL21381236 | 0.79 | ZDHHC20 (0.35) | TSHRZDHHC20ZDHHC2 | |
| SCHEMBL5483578 | 0.79 | ALDH1A1 (0.36) | TSHRZDHHC20ZDHHC2 | |
| SCHEMBL991089 | 0.79 | ZDHHC20 (0.35) | TSHRZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014147188-A1 | TEMPERATURE-RESPONSIVE CATALYSTS | EVONIK INDUSTRIES AG (DE) | 2014-09-25 | — | — | WO | disclosed |
| WO-2014147192-A1 | TEMPERATURE-RESPONSIVE CATALYSTS | EVONIK INDUSTRIES AG (DE) | 2014-09-25 | — | — | WO | disclosed |