Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | BRD2 | P25440 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | FBP1 | P09467 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16093740 | 0.82 | TSHR (0.52) | ALDH1A1ABCB1ABCC1BRD4BRD2 | |
| SCHEMBL6312572 | 0.82 | ABCB1 (0.60) | ALDH1A1ABCB1ABCC1MAPTLMNA | |
| SCHEMBL16120026 | 0.81 | ALDH1A1 (0.49) | ALDH1A1ABCB1ABCC1BRD4BRD2 | |
| SCHEMBL16093623 | 0.79 | ABCB1 (0.49) | ALDH1A1ABCB1ABCC1MAPTAKR1C3 | |
| SCHEMBL16120144 | 0.78 | ALDH1A1 (0.51) | ALDH1A1ABCB1ABCC1BRD4BRD2 | |
| SCHEMBL28048984 | 0.77 | TDP1 (0.53) | ALDH1A1MAPTFBP1MEN1KMT2A | |
| SCHEMBL16120145 | 0.77 | ALDH1A1 (0.50) | ALDH1A1ABCB1ABCC1MAPTFBP1 | |
| SCHEMBL16120142 | 0.77 | ALDH1A1 (0.50) | ALDH1A1ABCB1ABCC1MAPTFBP1 | |
| SCHEMBL2498033 | 0.76 | ALDH3A1 (0.44) | ALDH1A1MAPTFBP1MEN1KMT2A | |
| SCHEMBL16119989 | 0.75 | ALDH1A1 (0.51) | ALDH1A1ABCB1ABCC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160024083-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | HEALTH RESEARCH, INC. (US) | 2016-01-28 | — | — | US | disclosed |
| US-20160024083-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | HEALTH RESEARCH, INC. (US) | 2016-01-28 | — | — | US | disclosed |
| WO-2014153043-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | HEALTH RESEARCH, INC. (US) | 2014-09-25 | — | — | WO | disclosed |
| WO-2014153043-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | HEALTH RESEARCH, INC. (US) | 2014-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024083-A1 | COMPOUNDS AND METHODS FOR TREATING CANCERS | AR, KLK3, BRDT | ALDH1A1 371/4885ABCB1 1848/4885ABCC1 3822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.