Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 6/20 | 0.40 |
| ▸ | WEE1 | P30291 | 6/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16099437 | 0.90 | NPY5R (0.38) | CNR2ESR1ESR2POLB | |
| SCHEMBL16098994 | 0.88 | XDH (0.37) | CHEK1WEE1CNR2CDK1CCNB1 | |
| SCHEMBL16093856 | 0.80 | ATM (0.36) | CNR2TSHRMAPTATMALOX15 | |
| SCHEMBL16099208 | 0.78 | WEE1 (0.41) | CHEK1WEE1ESR1ESR2POLB | |
| SCHEMBL30940010 | 0.72 | DYRK1A (0.48) | — | |
| SCHEMBL16099657 | 0.72 | DYRK1A (0.48) | — | |
| SCHEMBL16123614 | 0.72 | HASPIN (0.47) | CHEK1WEE1CNR2ESR1ESR2 | |
| SCHEMBL30939941 | 0.72 | HASPIN (0.47) | CHEK1WEE1CNR2ESR1ESR2 | |
| SCHEMBL23234240 | 0.70 | ALDH1A1 (0.46) | CNR2TSHRTP53LMNAKDM4E | |
| SCHEMBL16123513 | 0.70 | CNR2 (0.41) | CNR2TSHRMAPTTP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968284-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | Osteoqc Inc. (CA) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014153203-A2 | ALKYL-AMINE HARMINE DERIVATIVES FOR PROMOTING BONE GROWTH | OSSIFI INC. (US) | 2014-09-25 | — | — | WO | disclosed |