SCHEMBL16098979

SCHEMBL16098979

Oc1nc2c(nc1Br)CCCC2

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
APAF1 O14727 1/20 0.34
NSD2 O96028 1/20 0.34
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.34
MAPT P10636 1/20 0.34
CASP3 P42574 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
ACHE P22303 2/20 0.31
MEN1 O00255 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9621309 0.70 NPC1 (0.43) KDM4EAPAF1NSD2ALDH1A1TP53
SCHEMBL2406021 0.67 ACHE (0.53) KDM4EAPAF1NSD2ALDH1A1TP53
SCHEMBL9014933 0.65 NPC1 (0.34) KDM4EAPAF1NSD2ALDH1A1TP53
SCHEMBL9621167 0.65 MEN1 (0.38) KDM4EAPAF1NSD2ALDH1A1TP53
SCHEMBL14572401 0.65 ACHE (0.55) KDM4EAPAF1NSD2ALDH1A1TP53
SCHEMBL20303200 0.63 PRNP (0.51) KDM4EALDH1A1MAPTTDP1L3MBTL1
SCHEMBL13197744 0.62 KDM4E (0.46) KDM4EAPAF1NSD2ALDH1A1TP53
SCHEMBL14380308 0.62 KDM4E (0.46) KDM4EAPAF1NSD2ALDH1A1TP53
SCHEMBL6419092 0.61 KDM4E (0.59) KDM4EAPAF1NSD2ALDH1A1TP53
SCHEMBL9014728 0.59 NPC1 (0.37) KDM4EAPAF1NSD2ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105051927-B Azabenzimidazole carbene ligands as efficiency enhancers in OLEDs UDC 爱尔兰有限责任公司 2020-10-16 CN disclosed
US-20190355917-A1 Organic Electroluminescent Element And Novel Iridium Complex UDC IRELAND LTD (IE) 2019-11-21 US disclosed
US-20190355917-A1 Organic Electroluminescent Element And Novel Iridium Complex UDC IRELAND LTD (IE) 2019-11-21 US disclosed
US-10374172-B2 Azabenzimidazole carbene complexes as efficiency booster in OLEDs UDC IRELAND LIMITED (IE) 2019-08-06 US disclosed
US-10374172-B2 Azabenzimidazole carbene complexes as efficiency booster in OLEDs UDC IRELAND LIMITED (IE) 2019-08-06 US disclosed
EP-2976793-B1 USE OF AZABENZIMIDAZOLE CARBENE COMPLEXES IN OLEDS UDC IRELAND LTD (IE) 2019-04-24 EP disclosed
EP-2976793-B1 USE OF AZABENZIMIDAZOLE CARBENE COMPLEXES IN OLEDS UDC IRELAND LTD (IE) 2019-04-24 EP disclosed
US-20160293862-A1 AZABENZIMIDAZOLE CARBENE COMPLEXES AS EFFICIENCY BOOSTER IN OLEDS BASF SE (DE) 2016-10-06 US disclosed
US-20160293862-A1 AZABENZIMIDAZOLE CARBENE COMPLEXES AS EFFICIENCY BOOSTER IN OLEDS BASF SE (DE) 2016-10-06 US disclosed
US-20160293862-A1 AZABENZIMIDAZOLE CARBENE COMPLEXES AS EFFICIENCY BOOSTER IN OLEDS BASF SE (DE) 2016-10-06 US disclosed
EP-2976793-A1 AZABENZIMIDAZOLE CARBENE COMPLEXES AS EFFICIENCY BOOSTER IN OLEDS BASF SE (DE) 2016-01-27 EP disclosed
WO-2014147134-A1 AZABENZIMIDAZOLE CARBENE COMPLEXES AS EFFICIENCY BOOSTER IN OLEDS BASF SE (DE) 2014-09-25 WO disclosed
WO-2014147134-A1 AZABENZIMIDAZOLE CARBENE COMPLEXES AS EFFICIENCY BOOSTER IN OLEDS BASF SE (DE) 2014-09-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10374172-B2 Azabenzimidazole carbene complexes as efficiency booster in OLEDs ICOS, OCIAD2, OXER1 KDM4E 3189/4885APAF1 4234/4885NSD2 1026/4885
US-20190355917-A1 Organic Electroluminescent Element And Novel Iridium Complex INCENP, TRPM6, L1CAM KDM4E 2304/4885APAF1 3878/4885NSD2 3732/4885
US-20160293862-A1 AZABENZIMIDAZOLE CARBENE COMPLEXES AS EFFICIENCY BOOSTER IN OLEDS ICOS, OCIAD2, OXER1 KDM4E 3189/4885APAF1 4234/4885NSD2 1026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.