Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28490982 | 0.85 | LMNA (0.40) | NAAAEPHX2SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL29046352 | 0.85 | NAAA (0.57) | NAAAEPHX2LMNAMEN1KMT2A | |
| SCHEMBL11319310 | 0.83 | NAAA (0.59) | NAAAEPHX2LMNAALDH1A1 | |
| SCHEMBL9138152 | 0.83 | NAAA (0.59) | NAAAEPHX2LMNAALDH1A1 | |
| SCHEMBL10822565 | 0.83 | NAAA (0.59) | NAAAEPHX2LMNAALDH1A1 | |
| SCHEMBL28417651 | 0.83 | NAAA (0.59) | NAAAEPHX2LMNAALDH1A1 | |
| SCHEMBL2537962 | 0.76 | NAAA (0.51) | NAAALMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL9150019 | 0.74 | NAAA (0.37) | NAAAEPHX2LMNAALDH1A1KMT2A | |
| SCHEMBL9789759 | 0.71 | NAAA (0.72) | NAAAEPHX1EPHX2GPR84FFAR1 | |
| SCHEMBL27975472 | 0.71 | KDM4E (0.33) | LMNAALDH1A1KDM4EMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014153113-A2 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF 3 AMINO-N-CYCLOPROPYL-2 HYDROXYPROPIONAMIDE DERIVATIVES | VIROBAY, INC. (US) | 2014-09-25 | — | — | WO | claimed |