Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577009 | 0.84 | MAPT (0.50) | MAPTGAAHSD17B10TP53ALOX15 | |
| SCHEMBL30790667 | 0.83 | MAPT (0.74) | MAPTGAAHSD17B10TP53ALOX15 | |
| SCHEMBL112507 | 0.83 | MAPT (0.74) | MAPTGAAHSD17B10TP53ALOX15 | |
| SCHEMBL8764887 | 0.81 | MAPT (0.71) | MAPTGAAHSD17B10TP53ALOX15 | |
| Hydrochloric Acid SCHEMBL11745887 | 0.81 | MAPT (0.71) | MAPTGAAHSD17B10TP53ALOX15 | |
| Ammonia Solution, Strong SCHEMBL10992665 | 0.81 | MAPT (0.71) | MAPTGAAHSD17B10TP53ALOX15 | |
| SCHEMBL6143249 | 0.77 | CES2 (0.52) | GAAALDH1A1RECQLNPC1RAB9A | |
| SCHEMBL64069 | 0.76 | AKR1C3 (0.57) | MAPTGAAHSD17B10ALDH1A1KDM4E | |
| SCHEMBL1331831 | 0.76 | AKR1C3 (0.57) | MAPTGAAHSD17B10ALDH1A1KDM4E | |
| SCHEMBL2171273 | 0.75 | NPC1 (0.60) | MAPTGAAHSD17B10ALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968670-A1 | COATING FOR A SURFACE | W. L. Gore & Associates, Inc. (US) | 2016-01-20 | — | — | EP | claimed |
| WO-2014152378-A1 | COATING FOR A SURFACE | W.L. GORE & ASSOCIATES, INC. (US) | 2014-09-25 | — | — | WO | claimed |