Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | ESRRA | P11474 | 3/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16099810 | 0.84 | MAPT (0.52) | MAPTGAAHSD17B10ALDH1A1CA1 | |
| SCHEMBL16099809 | 0.84 | MAPT (0.55) | MAPTGAAHSD17B10TP53ALOX15 | |
| SCHEMBL5575993 | 0.77 | PBRM1 (0.54) | MAPTGAAHSD17B10ALDH1A1CA1 | |
| SCHEMBL30790667 | 0.74 | MAPT (0.74) | MAPTGAAHSD17B10TP53ALOX15 | |
| SCHEMBL112507 | 0.74 | MAPT (0.74) | MAPTGAAHSD17B10TP53ALOX15 | |
| SCHEMBL23881551 | 0.73 | MAPT (0.55) | MAPTGAAHSD17B10TP53ALOX15 | |
| SCHEMBL30089335 | 0.73 | MAPT (0.55) | MAPTGAAHSD17B10TP53ALOX15 | |
| Hydrochloric Acid SCHEMBL11745887 | 0.72 | MAPT (0.71) | MAPTGAAHSD17B10TP53ALOX15 | |
| Ammonia Solution, Strong SCHEMBL10992665 | 0.72 | MAPT (0.71) | MAPTGAAHSD17B10TP53ALOX15 | |
| SCHEMBL8764887 | 0.72 | MAPT (0.71) | MAPTGAAHSD17B10TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1634079-A1 | SCREENING METHOD FOR SUBSTANCES BINDING TO MEROZOITE SURFACE PROTEIN-1/42 | MEDICAL RESEARCH COUNCIL (GB) | 2006-03-15 | — | — | EP | claimed |
| WO-2004113920-A1 | SCREENING METHOD FOR SUBSTANCES BINDING TO MEROZOITE SURFACE PROTEIN-1/42 | MEDICAL RESEARCH COUNCIL (GB) | 2004-12-29 | — | — | WO | claimed |
| US-20070003987-A1 | Screening method for substance binding to merozoite surface protein-1/42 | MEDICAL RESEARCH COUNCIL (GB) | 2007-01-04 | — | — | US | disclosed |
| WO-1994013277-A2 | USE OF DINAPHTHALENES COMPOUNDS AS ANTIPROLIFERATIVE AGENTS | IMPERIAL CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070003987-A1 | Screening method for substance binding to merozoite surface protein-1/42 | CD2BP2, MASP2, CD14 | MAPT 4427/4885GAA 3513/4885HSD17B10 4047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.