Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Valine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.79 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 2/20 | 0.37 |
| ▸ | GABRD | O14764 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.37 |
| ▸ | GABRE | P78334 | 2/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL3967257 | 1.00 | SLC7A5 (0.79) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| Valine SCHEMBL9596645 | 0.91 | SLC7A5 (0.65) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| Valine SCHEMBL30099875 | 0.90 | SLC7A5 (0.71) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| Valine SCHEMBL10351713 | 0.90 | SLC7A5 (0.79) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| Valine SCHEMBL11876966 | 0.90 | SLC7A5 (0.79) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| Valine SCHEMBL15656624 | 0.90 | SLC7A5 (0.79) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| Valine SCHEMBL10718697 | 0.89 | SLC7A5 (0.62) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| Valine SCHEMBL1813972 | 0.89 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| Valine SCHEMBL8516 | 0.89 | — | — | |
| Valine SCHEMBL41225 | 0.89 | SLC7A5 (1.00) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 551 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118207574-A | Nanometer flower spherical foam nickel-supported Pd catalyst and preparation method and application thereof | 德清县浙工大莫干山研究院 | 2024-06-18 | — | — | CN | claimed |
| CN-117783260-A | Method for detecting chelation rate of polypeptide copper chelate | 南京金斯瑞生物科技有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-117747004-A | Lignin co-production life cycle evaluation method based on bioethanol production by straw | 常州大学 | 2024-03-22 | — | — | CN | claimed |
| CN-115536505-B | Copper-catalyzed regioselective iodination of terminal alkynes to (E) -beta-iodo-alpha, beta-unsaturated aldehydes | 湖南大学 | 2023-10-24 | — | — | CN | claimed |
| CN-114841243-B | Cross-modal retrieval model training method, cross-modal retrieval method, device and medium | 中国科学院上海高等研究院 | 2023-04-07 | — | — | CN | claimed |
| CN-115536505-A | Copper-catalyzed regioselective iodination of terminal alkynes to (E) -beta-iodo-alpha, beta-unsaturated aldehydes | 湖南大学 | 2022-12-30 | — | — | CN | claimed |
| CN-115470543-A | Stress analysis and calculation method for hydraulic engineering structure under wet-heat condition | 三峡大学 | 2022-12-13 | — | — | CN | claimed |
| CN-114660033-A | Method for rapidly detecting thyroxine T4 based on fluorescence resonance transfer | 武汉海关技术中心 | 2022-06-24 | — | — | CN | claimed |
| CN-109608397-B | Compound capable of blocking heavy metal absorption of plants and composition thereof | 四川惠泰农业科技有限公司 | 2021-07-02 | — | — | CN | claimed |
| CN-110205122-B | Controllable synthesis ultra-bright panchromatic carbon dot for finely regulating crystal morphology and application | 四川中科微纳科技有限公司 | 2020-08-11 | — | — | CN | claimed |
| CN-101304972-B | Process for preparing pyridylcarboxylic amides and esters | BASF SE | 2011-08-17 | — | — | CN | claimed |
| US-7692020-B2 | Process for the preparation of pyridylcarboxylic amides and esters | BASF SE (DE) | 2010-04-06 | — | — | US | claimed |
| EP-1948609-B1 | PROCESS FOR THE PREPARATION OF PYRIDYLCARBOXYLIC AMIDES AND ESTERS | BASF SE (DE) | 2010-03-10 | — | — | EP | claimed |
| CN-101304972-A | Process for preparing pyridylcarboxylic amides and esters | BASF AG (DE) | 2008-11-12 | — | — | CN | claimed |
| US-20080249313-A1 | Process for the Preparation of Pyridylcarboxylic Amides and Esters | BASF SE (DE) | 2008-10-09 | — | — | US | claimed |
| EP-1948609-A1 | PROCESS FOR THE PREPARATION OF PYRIDYLCARBOXYLIC AMIDES AND ESTERS | BASF SE (DE) | 2008-07-30 | — | — | EP | claimed |
| WO-2007051759-A1 | PROCESS FOR THE PREPARATION OF PYRIDYLCARBOXYLIC AMIDES AND ESTERS | BASF SE (DE) | 2007-05-10 | — | — | WO | claimed |
| EP-0378089-B1 | Method for the preparation of 2-amino-4-fluoropyrimidine derivatives | BASF AG (DE) | 1994-06-29 | — | — | EP | claimed |
| US-5011927-A | Preparation of 2-amino-4-fluoropyrimidine derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1991-04-30 | — | — | US | claimed |
| EP-0378089-A1 | Method for the preparation of 2-amino-4-fluoropyrimidine derivatives | BASF Aktiengesellschaft (DE) | 1990-07-18 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080249313-A1 | Process for the Preparation of Pyridylcarboxylic Amides and Esters | ADH1C, ADH1A, CBR1 | SLC7A5 3963/4885SLC1A3 3523/4885SLC1A2 3050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.