Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | IDE | P14735 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR1F | P30939 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17457576 | 0.85 | HTR6 (0.45) | HTR6ESR2IDEHTR1AHTR1D | |
| SCHEMBL16120066 | 0.80 | HTR6 (0.41) | HTR6ALDH1A1 | |
| SCHEMBL16102368 | 0.78 | HTR6 (0.43) | HTR6ESR2SRCIDEHTR1A | |
| SCHEMBL16099896 | 0.72 | HTR6 (0.42) | HTR6ESR2SRCESR1MEN1 | |
| SCHEMBL17457571 | 0.72 | HTR6 (0.36) | HTR6MEN1KMT2A | |
| SCHEMBL17457568 | 0.69 | MAPT (0.35) | HTR6MEN1KMT2AALDH1A1 | |
| SCHEMBL3040501 | 0.63 | IDE (0.55) | HTR6IDEALDH1A1SLC9A1 | |
| SCHEMBL5504710 | 0.63 | HTR6 (1.00) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL22915922 | 0.61 | KLK7 (0.43) | HTR6MEN1KMT2AALDH1A1SLC9A1 | |
| SCHEMBL19737377 | 0.61 | HTR6 (0.59) | HTR6HTR1AHTR1DHTR1BHTR1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970220-A2 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014153235-A2 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-09-25 | — | — | WO | disclosed |