Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | GPR6 | P46095 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1609505 | 0.87 | SLC6A3 (0.41) | SLC6A3S1PR4CNR2MRGPRX4PDE10A | |
| SCHEMBL1609110 | 0.78 | HPGD (0.50) | SLC6A3S1PR4PDE10AALDH1A1SMN1; SMN2 | |
| SCHEMBL1610893 | 0.78 | PDE4B (0.36) | SLC6A3CNR2MRGPRX4PDE10AALDH1A1 | |
| SCHEMBL1610298 | 0.76 | SLC6A3 (0.39) | SLC6A3S1PR4CNR2MRGPRX4PDE10A | |
| SCHEMBL1610988 | 0.75 | HPGD (0.40) | SLC6A3PDE10AHPGDNPSR1 | |
| SCHEMBL1608948 | 0.74 | KMT2A (0.37) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL1609147 | 0.74 | PDE10A (0.50) | SLC6A3PDE10AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL12713056 | 0.73 | CBLB (0.36) | SLC6A3PDE10AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL12712720 | 0.73 | PDE10A (0.49) | PDE10AHTT | |
| SCHEMBL1609781 | 0.72 | ABL1 (0.45) | PDE10AALDH1A1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | SLC6A3 2437/4885S1PR4 3589/4885CNR2 1000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.