SCHEMBL161022

SCHEMBL161022

[c]1cc2cc3ccccc3cc2s1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
CYP3A4 P08684 2/20 0.33
HSD17B10 Q99714 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
ALOX15 P16050 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
HBB P68871 1/20 0.33
HIF1A Q16665 1/20 0.33
GLA P06280 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
ACHE P22303 1/20 0.32
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
NQO2 P16083 1/20 0.31
CYP2A6 P11509 5/20 0.30
ALOX12 P18054 1/20 0.30
CYP1A2 P05177 2/20 0.30
CA7 P43166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4083703 0.98 ALDH1A1 (0.37) ALDH1A1CYP3A4HSD17B10TDP1ALOX15
SCHEMBL169044 0.85
SCHEMBL851944 0.83
SCHEMBL2173 0.78
SCHEMBL455460 0.78
Water SCHEMBL28146617 0.76 CYP2A6 (0.33) CYP2A6ALOX12CA9
SCHEMBL28067652 0.76 CYP2A6 (0.33) CYP2A6ALOX12CA9
SCHEMBL21858595 0.75 CASP6 (0.45) ALDH1A1CYP3A4HSD17B10ALOX15CASP1
SCHEMBL21858492 0.75 CASP6 (0.45) ALDH1A1CYP3A4HSD17B10ALOX15CASP1
SCHEMBL15169446 0.74 DYRK1A (0.38) CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3606 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399199-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS Reuter Chemische Apparatebau e.K. (DE) 2024-07-17 EP claimed
EP-4399200-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS Mitsubishi Gas Chemical Company, Inc. (JP) 2024-07-17 EP claimed
WO-2023213965-A1 INHIBITORS OF CDK8 AND CDK19 UNIVERSITY OF DUNDEE (GB) 2023-11-09 WO claimed
WO-2023038156-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-03-16 WO claimed
WO-2023036868-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS REUTER CHEMISCHE APPARATEBAU E.K. (DE) 2023-03-16 WO claimed
US-11198757-B2 Compositions including a photolatent amine, camphorquinone, and coumarin and related methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-12-14 US claimed
US-11090681-B2 Composition including a polythiol, a polyepoxide, a photolatent base, and an amine and methods relating to the composition 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-08-17 US claimed
US-20200385370-A1 APPARATUS FOR REMOVING BAD ODOR FROM TOILET SYNBLIA THERAPEUTICS, INC. 2020-12-10 US claimed
EP-3704104-A1 IRAK4 INHIBITORS AND USES THEREOF Synblia Therapeutics, Inc. (US) 2020-09-09 EP claimed
US-20190276588-A1 COMPOSITION INCLUDING A POLYTHIOL, A POLYEPOXIDE, A PHOTOLATENT BASE, AND AN AMINE AND METHODS RELATING TO THE COMPOSITION 3M INNOVATIVE PROPERTIES COMPANY 2019-09-12 US claimed
WO-1999067232-A2 PROCESS FOR THE PREPARATION OF 3-ARYL-BENZOFURANONES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-12-29 WO claimed
WO-1999048997-A1 STABILISATION OF ORGANIC MATERIALS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-09-30 WO claimed
EP-0857765-A2 Stabilizing agents for powder paints Ciba SC Holding AG (CH) 1998-08-12 EP claimed
WO-1998032756-A1 SUBSTITUTED AMINOALKYLIDENAMINO TRIAZINES AS HERBICIDES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-07-30 WO claimed
EP-0842975-A1 Stabilising polyolefins for long term contact with an extracting medium Ciba SC Holding AG (CH) 1998-05-20 EP claimed
EP-0839623-A1 Stabiliser combination for rotomolding process Ciba SC Holding AG (CH) 1998-05-06 EP claimed
US-5652368-A NERVOUS SYSTEM DISORDERS, ALZHEIMER'S DISEASE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1997-07-29 US claimed
US-5607624-A Process for the preparation of 3-arylbenzofuranones CIBA-GEIGY CORPORATION (US) 1997-03-04 US claimed
US-5475007-A Preventing convulsions THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-12-12 US claimed
EP-0648765-A1 Process for the production of 3-arylbenzofuranones CIBA-GEIGY AG (CH) 1995-04-19 EP claimed