Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.51 |
| ▸ | PDE4A | P27815 | 2/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1610085 | 0.83 | CHRM3 (0.55) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1610230 | 0.82 | CHRM3 (0.53) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1609486 | 0.74 | CHRM3 (0.57) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1610420 | 0.74 | ALDH1A1 (0.38) | PDE10AHSD17B10HPGDKMT2ATSHR | |
| SCHEMBL1610082 | 0.68 | ERCC1 (0.34) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1611084 | 0.67 | PDE10A (0.60) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1609744 | 0.67 | PDE10A (0.39) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1611392 | 0.67 | PDE10A (0.44) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1609704 | 0.66 | PDE10A (0.62) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1610084 | 0.66 | PDE10A (0.56) | PDE10ACYP3A4CYP2D6KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | CHRM3 2705/4885PDE4A 1115/4885PDE4B 1132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.