Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 18/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1609068 | 0.84 | PDE10A (0.44) | PDE10ANR1I2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL1610085 | 0.82 | CHRM3 (0.55) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL1608875 | 0.82 | ALDH1A1 (0.51) | PDE10ACYP3A4PDE4AALDH1A1SMN1; SMN2 | |
| SCHEMBL1609763 | 0.81 | PDE10A (0.47) | PDE10ANR1I2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL1610382 | 0.80 | PDE10A (0.44) | PDE10ACHRM3PDE4APDE4BPDE4C | |
| SCHEMBL1610277 | 0.80 | PDE10A (0.44) | PDE10ANR1I2CYP3A4CYP2D6CHRM3 | |
| SCHEMBL1610305 | 0.80 | PDE10A (0.44) | PDE10AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL1609110 | 0.80 | HPGD (0.50) | PDE10AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL1609704 | 0.80 | PDE10A (0.62) | PDE10ACYP3A4CHRM3PDE4APDE4B | |
| SCHEMBL1609687 | 0.80 | PDE10A (0.45) | PDE10ANR1I2CYP3A4CYP2D6CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | PDE10A 1704/4885NR1I2 3289/4885CYP3A4 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.