Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TYMP | P19971 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16102333 | 0.75 | L3MBTL1 (0.36) | L3MBTL1TYMP | |
| SCHEMBL14478237 | 0.65 | TYMP (0.45) | L3MBTL1TYMP | |
| SCHEMBL21067903 | 0.64 | TYMP (0.39) | L3MBTL1TYMP | |
| SCHEMBL6570508 | 0.63 | TYMP (0.46) | L3MBTL1TYMP | |
| SCHEMBL20599949 | 0.62 | TYMP (0.45) | TYMP | |
| SCHEMBL14709896 | 0.62 | TYMP (0.47) | L3MBTL1TYMPALDH1A1HPGD | |
| SCHEMBL7757620 | 0.61 | TYMP (0.41) | TYMPALDH1A1HPGD | |
| SCHEMBL4315838 | 0.61 | KDM4E (0.43) | L3MBTL1TYMP | |
| SCHEMBL9007002 | 0.60 | TYMP (0.43) | L3MBTL1TYMPALDH1A1 | |
| SCHEMBL13957603 | 0.60 | GRIA1 (0.46) | TYMPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970945-B1 | IMPROVED THYMIDINE KINASE GENE | GENVIVO INC (US) | 2024-05-01 | — | — | EP | disclosed |
| US-11253611-B2 | Thymidine kinase diagnostic assay for gene therapy applications | Genvivo, Inc. (US) | 2022-02-22 | — | — | US | disclosed |
| EP-2967078-A1 | THYMIDINE KINASE DIAGNOSTIC ASSAY FOR GENE THERAPY APPLICATIONS | Epeius Biotechnologies Corporation (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2970945-A2 | IMPROVED THYMIDINE KINASE GENE | Epeius Biotechnologies Corporation (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014153258-A2 | IMPROVED THYMIDINE KINASE GENE | EPEIUS BIOTECHNOLOGIES CORPORATION (US) | 2014-09-25 | — | — | WO | disclosed |
| WO-2014153205-A1 | THYMIDINE KINASE DIAGNOSTIC ASSAY FOR GENE THERAPY APPLICATIONS | EPEIUS BIOTECHNOLOGIES CORPORATION (US) | 2014-09-25 | — | — | WO | disclosed |