Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 3/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | CBLB | Q13191 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1609780 | 0.87 | ADORA2A (0.40) | PDE10ASLC6A3TSHRALDH1A1HSD17B10 | |
| SCHEMBL1610062 | 0.82 | PDE2A (0.40) | SLC6A3ALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL1611006 | 0.82 | PDE10A (0.41) | PDE10A | |
| SCHEMBL12712709 | 0.79 | SLC6A3 (0.40) | SLC6A3ALDH1A1HSD17B10KDM4EGAA | |
| SCHEMBL1611017 | 0.79 | PDE2A (0.38) | PDE10ASLC6A3HSD17B10KDM4E | |
| SCHEMBL1610460 | 0.75 | VNN1 (0.37) | PDE10AALDH1A1SMN1; SMN2 | |
| SCHEMBL1610679 | 0.75 | SLC6A3 (0.39) | PDE10ASLC6A3TSHRALDH1A1HSD17B10 | |
| SCHEMBL1610682 | 0.75 | SLC6A3 (0.39) | PDE10ASLC6A3TSHRALDH1A1HSD17B10 | |
| SCHEMBL12713074 | 0.74 | PDE10A (0.35) | PDE10ASLC6A3TSHRALDH1A1HSD17B10 | |
| SCHEMBL1610775 | 0.74 | PDE10A (0.35) | PDE10ASLC6A3TSHRALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | FPR2 3559/4885PDE10A 1704/4885SLC6A3 2437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.