Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 4/20 | 0.37 |
| ▸ | JAK2 | O60674 | 3/20 | 0.37 |
| ▸ | TYK2 | P29597 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10817263 | 0.76 | GABRA1 (0.38) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10876877 | 0.76 | TYK2 (0.37) | JAK2TYK2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL11382521 | 0.75 | TYK2 (0.44) | ALDH1A1TYK2MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL11374694 | 0.73 | TYK2 (0.43) | ALDH1A1TYK2MEN1KMT2AMAPT | |
| SCHEMBL11559044 | 0.72 | CES2 (0.39) | ALDH1A1HPGDNPC1JAK1JAK2 | |
| SCHEMBL11245746 | 0.72 | CYP3A4 (0.31) | ALDH1A1CYP3A4MAPT | |
| Hydrochloric Acid SCHEMBL11564697 | 0.71 | CES2 (0.38) | ALDH1A1HPGDNPC1JAK1JAK2 | |
| SCHEMBL11369766 | 0.71 | MEN1 (0.51) | ALDH1A1HPGDNPC1MEN1KMT2A | |
| SCHEMBL11449564 | 0.70 | CYP1A2 (0.46) | ALDH1A1HPGDNPC1MEN1KMT2A | |
| SCHEMBL11480277 | 0.69 | GAA (0.40) | HPGDNPC1JAK1JAK2TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160272729-A1 | METHOD OF TREATING A PATHOLOGICAL SYNDROME AND A PHARMACEUTICAL AGENT | EPSHTEIN OLEG ILIICH (RU) | 2016-09-22 | — | — | US | disclosed |
| US-20160229914-A1 | METHOD OF TREATING A PATHOLOGICAL SYNDROME | EPSHTEIN OLEG ILIICH (RU) | 2016-08-11 | — | — | US | disclosed |
| US-9382332-B2 | Method of treating a pathological syndrome and a pharmaceutical agent | OLEG ILIICH EPSHTEIN (RU) | 2016-07-05 | — | — | US | disclosed |
| US-20160184256-A1 | METHOD OF TREATING DISORDERS OF THE CARDIOVASCULAR SYSTEM AND A PHARMACEUTICAL AGENT | EPSHTEIN OLEG ILIICH (RU) | 2016-06-30 | — | — | US | disclosed |
| US-20160176987-A1 | METHOD OF TREATING A PATHOLOGICAL SYNDROME AND A PHARMACEUTICAL AGENT | EPSHTEIN OLEG ILIICH (RU) | 2016-06-23 | — | — | US | disclosed |
| US-20160137750-A1 | METHOD OF TREATING A PATHOLOGICAL SYNDROME | EPSHTEIN OLEG IIIICH (RU) | 2016-05-19 | — | — | US | disclosed |
| US-9303091-B2 | Method of treating disorders of the cardiovascular system and a pharmaceutical agent | Epshtein, Oleg Iliich (RU) | 2016-04-05 | — | — | US | disclosed |
| US-9303090-B2 | Method of treating a pathological syndrome and a pharmaceutical agent | Epshtein, Oleg Iliich (RU) | 2016-04-05 | — | — | US | disclosed |
| US-9273117-B2 | Method for administering homeopathically potentized antibody | OLEG ILIICH EPSHTEIN (RU) | 2016-03-01 | — | — | US | disclosed |
| US-9228024-B2 | Method of treating hypertension disorder and a pharmaceutical agent | EPSHTEIN, OLEG I. (RU) | 2016-01-05 | — | — | US | disclosed |
| US-20070224187-A1 | Method of treating a pathological syndrome and a pharmaceutical agent | EPSHTEIN, OLEG I. (RU) | 2007-09-27 | — | — | US | disclosed |
| US-20030099636-A1 | Curing method for pathologic syndrome and medicinal preparation | EPSHTEIN, OLEG I. (RU) | 2003-05-29 | — | — | US | disclosed |
| EP-1295606-A1 | CURING METHOD FOR PATHOLOGIC SYNDROME AND A MEDICINAL PREPARATION | Epshtein, Oleg Iliich (RU) | 2003-03-26 | — | — | EP | disclosed |
| EP-0081923-B1 | 2-(TRISUBSTITUTED PHENYLIMINO)-IMIDAZOLINES | ALCON LABORATORIES, INC. (US) | 1987-01-21 | — | — | EP | disclosed |
| EP-0081924-B1 | TOPICAL COMPOSTIONS FOR LOWERING INTRAOCULAR PRESSURE | ALCON LABORATORIES, INC. (US) | 1986-02-19 | — | — | EP | disclosed |
| US-4517199-A | TREATMENT OF GLAUCOMA | ALCON LABORATORIES, INC. (US) | 1985-05-14 | — | — | US | disclosed |
| US-4515800-A | GLAUCOMA | ALCON MANUFACTURING, LTD. | 1985-05-07 | — | — | US | disclosed |
| US-4461904-A | 2-(Trisubstituted phenylimino)-imidazolines | ALCON LABORATORIES, INC. (US) | 1984-07-24 | — | — | US | disclosed |
| EP-0081924-A1 | Topical compostions for lowering intraocular pressure | ALCON LABORATORIES, INC. (US) | 1983-06-22 | — | — | EP | disclosed |
| EP-0081923-A2 | 2-(Trisubstituted phenylimino)-imidazolines | ALCON LABORATORIES, INC. (US) | 1983-06-22 | — | — | EP | disclosed |