Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17700462 | 0.81 | ALDH1A1 (0.41) | OPRM1RORCOPRL1KDM4EALDH1A1 | |
| SCHEMBL16827186 | 0.77 | TACR1 (0.48) | KDM4ETSHR | |
| SCHEMBL17978299 | 0.77 | DPP7 (0.41) | OPRM1CHRM2RORCOPRL1KDM4E | |
| SCHEMBL28496874 | 0.70 | GRIN2B (0.46) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL12469662 | 0.69 | OPRM1 (0.68) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL8261420 | 0.69 | OPRM1 (0.56) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL28793512 | 0.68 | OPRM1 (0.51) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL2629504 | 0.68 | ALDH1A1 (0.62) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL1292476 | 0.67 | GRIN2D (0.39) | OPRM1GRIN2DGRIN3BCHRM2CHRM1 | |
| SCHEMBL16039169 | 0.67 | KDM4E (0.36) | OPRM1RORCOPRL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2976337-A1 | 5-AMINO-QUINOLINE-8-CARBOXAMIDE DERIVATIVES AS 5-HT4 RECEPTOR AGONISTS | Suven Life Sciences Limited (IN) | 2016-01-27 | — | — | EP | disclosed |
| WO-2014147636-A1 | 5-AMINO-QUINOLINE-8-CARBOXAMIDE DERIVATIVES AS 5-HT4 RECEPTOR AGONISTS | SUVEN LIFE SCIENCES LIMITED (IN) | 2014-09-25 | — | — | WO | disclosed |