Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MPI | P34949 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6797539 | 0.89 | KDM4E (0.48) | BCL2CYP19A1CYP11B2SIGMAR1KDM4E | |
| SCHEMBL29392039 | 0.77 | MAOB (0.54) | CYP19A1KDM4EALDH1A1MAOBACHE | |
| SCHEMBL251842 | 0.77 | MAOB (0.54) | CYP19A1KDM4EALDH1A1MAOBACHE | |
| SCHEMBL31167959 | 0.77 | MAPT (0.51) | BCL2CYP19A1CYP11B2SIGMAR1KDM4E | |
| SCHEMBL356453 | 0.77 | MAPT (0.51) | BCL2CYP19A1CYP11B2SIGMAR1KDM4E | |
| SCHEMBL31147657 | 0.77 | MAPT (0.51) | BCL2CYP19A1CYP11B2SIGMAR1KDM4E | |
| SCHEMBL5969900 | 0.77 | MAPT (0.51) | BCL2CYP19A1CYP11B2SIGMAR1KDM4E | |
| SCHEMBL356454 | 0.77 | MAPT (0.51) | BCL2CYP19A1CYP11B2SIGMAR1KDM4E | |
| SCHEMBL2315390 | 0.76 | SIGMAR1 (0.68) | BCL2CYP19A1CYP11B2SIGMAR1KDM4E | |
| SCHEMBL2607471 | 0.74 | DRD1 (0.62) | BCL2SIGMAR1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
| EP-2237669-A2 | CHEMICAL COMPOUNDS | Syngenta Limited (GB) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009081112-A2 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | BCL2 449/4885CYP19A1 309/4885CYP11B2 650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.