Sugi Predict

Sugi Predict / Compounds / SCHEMBL251842

SCHEMBL251842

SCHEMBL251842

COc1ccc2c(c1)C(=O)CC2

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 1/20 0.54
▸ PBRM1 Q86U86 1/20 0.53
▸ METAP1 P53582 2/20 0.53
▸ ACHE P22303 1/20 0.53
▸ KDM4E B2RXH2 1/20 0.51
▸ HTT P42858 1/20 0.51
▸ HRH3 Q9Y5N1 2/20 0.51
▸ CYP19A1 P11511 1/20 0.51
▸ MAPK14 Q16539 1/20 0.50
▸ BRD4 O60885 1/20 0.50
▸ TYMS P04818 1/20 0.50
▸ NPC1 O15118 1/20 0.49
▸ ALDH1A1 P00352 1/20 0.49
▸ LMNA P02545 1/20 0.49
▸ RAB9A P51151 1/20 0.49
▸ SMN1; SMN2 Q16637 1/20 0.49
▸ NPSR1 Q6W5P4 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29392039 1.00 MAOB (0.54) MAOBPBRM1METAP1ACHEKDM4E
SCHEMBL6130607 0.93 MAPK14 (0.56) MAOBMETAP1KDM4EHTTCYP19A1
Butane SCHEMBL4688097 0.93 BRD4 (0.52) MAOBPBRM1METAP1ACHEKDM4E
Acetic Acid SCHEMBL6934641 0.92 MAOB (0.51) MAOBPBRM1METAP1ACHEKDM4E
SCHEMBL29726357 0.89 MAOB (0.58) MAOBMETAP1ACHEKDM4EHTT
SCHEMBL5146484 0.89 MAOB (0.58) MAOBMETAP1ACHEKDM4EHTT
SCHEMBL5871789 0.89 MAOB (0.58) MAOBMETAP1ACHECYP19A1MAPK14
SCHEMBL120284 0.89 MAOB (0.58) MAOBMETAP1ACHEKDM4EHTT
SCHEMBL3860885 0.86 MAPK14 (0.50) MAOBMETAP1CYP19A1MAPK14
SCHEMBL21177474 0.86 BRD4 (0.48) MAOBPBRM1KDM4EHTTHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 803 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113861113-B Preparation and application of fused ring pyridine compound and derivative thereof 中国科学院福建物质结构研究所 2022-12-06 — — CN claimed
CN-114133376-A Organic solar cell receptor material, preparation method thereof and organic solar cell 北京师范大学 2022-03-04 — — CN claimed
CN-113861113-A Preparation and application of fused ring pyridine compound and derivative thereof 中国科学院福建物质结构研究所 2021-12-31 — — CN claimed
CN-112574078-A 2-sulfuryl-2, 3-dihydro-1-indanone and derivatives and synthesis method thereof 湖南工程学院 2021-03-30 — — CN claimed
US-10092786-B2 Fire extinguishing composition comprising aldoketones compound XI'AN WESTPEACE FIRE TECHNOLOGY CO., LTD. (CN) 2018-10-09 — — US claimed
US-20160332016-A1 Fire Extinguishing Composition Comprising Aldoketones Compound NANO FIRE, LLC 2016-11-17 — — US claimed
US-5663029-A DEVELOPMENT OF LATENT IMAGE, TRANSFERRING TO FORM RECORDING SHEETS, COATING A SUBSTRATE USING POLYMERS XEROX CORPORATION (US) 1997-09-02 — — US claimed
US-5618982-A SIMPLE INDUSTRIAL PROCESS OF CATALYZING IN PRESENCE OF METALLIC PHOSPHATES RHONE-POULENC CHIMIE (FR) 1997-04-08 — — US claimed
EP-4745117-A1 NOVEL INDENONE DERIVATIVE AND USE THEREOF Amyloid Solution Inc. (KR) 2026-05-20 — — EP disclosed
US-12559486-B2 Tau-protein targeting compounds and associated methods of use ARVINAS OPERATIONS, INC. (US) 2026-02-24 — — US disclosed
EP-4688772-A1 BIARYL DERIVATIVES AND RELATED USES Moma Therapeutics, Inc. (US) 2026-02-11 — — EP disclosed
US-20260015360-A1 BIARYL DERIVATIVES AND RELATED USES MOMA THERAPEUTICS, INC. 2026-01-15 — — US disclosed
US-20250289789-A1 REVERSIBLE LYSINE COVALENT MODIFIERS OF CDK2 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. 2025-09-18 — — US disclosed
US-20250223285-A1 NOVEL HETEROCYCLIC DERIVATIVES USEFUL AS SHP2 INHIBITORS JACOBIO PHARMACEUTICALS CO LTD (CN) 2025-07-10 — — US disclosed
US-4258054-A ANTIDIABETIC PFIZER INC. (US) 1981-03-24 — — US disclosed
US-4210756-A Tetrahydroquinoline hydantoins for chronic diabetic complications PFIZER INC. (US) 1980-07-01 — — US disclosed
US-4209630-A ANTIDIABETIC AGENTS PFIZER INC. (US) 1980-06-24 — — US disclosed
US-4147795-A ENZYME INHIBITORS PFIZER INC. (US) 1979-04-03 — — US disclosed
US-4117230-A ANTIDIABETIC AGENTS PFIZER INC. (US) 1978-09-26 — — US disclosed
US-4107324-A ARTHROPODICIDES, FUNGICIDES BAYER AKTIENGESELLSCHAFT (DE) 1978-08-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015360-A1 BIARYL DERIVATIVES AND RELATED USES POLB, POLA1, POLN MAOB 1016/4885PBRM1 155/4885METAP1 1952/4885
US-20250289789-A1 REVERSIBLE LYSINE COVALENT MODIFIERS OF CDK2 AND USES THEREOF CDK2, CDK20, CDK1 MAOB 1305/4885PBRM1 1655/4885METAP1 3202/4885
US-20250223285-A1 NOVEL HETEROCYCLIC DERIVATIVES USEFUL AS SHP2 INHIBITORS PTPN5, PTPN1, PTPRJ MAOB 3802/4885PBRM1 1662/4885METAP1 1981/4885
US-12559486-B2 Tau-protein targeting compounds and associated methods of use UBQLN2, UBQLN1, CRBN MAOB 3498/4885PBRM1 76/4885METAP1 1740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.