Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 12/20 | 0.47 |
| ▸ | PRKG1 | Q13976 | 9/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 3/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1610339 | 1.00 | ROCK2 (0.47) | ROCK2PRKG1POLBPDE10ASMN1; SMN2 | |
| SCHEMBL12712871 | 0.89 | PDE10A (0.46) | PDE10A | |
| SCHEMBL12712886 | 0.89 | PDE10A (0.46) | PDE10A | |
| SCHEMBL1610839 | 0.88 | PDE10A (0.48) | PDE10AMEN1KMT2AIDH1CYP2C9 | |
| SCHEMBL1610842 | 0.88 | PDE10A (0.48) | PDE10AMEN1KMT2AIDH1CYP2C9 | |
| SCHEMBL1610170 | 0.88 | PDE10A (0.50) | PDE10AIDH1 | |
| SCHEMBL1610091 | 0.87 | P2RX3 (0.46) | PDE10AMEN1KMT2A | |
| SCHEMBL1609464 | 0.86 | SOS1 (0.47) | — | |
| SCHEMBL1609803 | 0.83 | PDE10A (0.50) | PDE10ASMN1; SMN2IDH1 | |
| SCHEMBL12738177 | 0.83 | ROCK2 (0.43) | ROCK2PRKG1POLBPDE10ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110086759-A1 | CHEMICAL COMPOUNDS | DDT, PNPO, CBR3 | ROCK2 3345/4885PRKG1 1512/4885POLB 915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.