Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13151574 | 1.00 | ALOX15 (0.43) | ALOX15TSHRANPEPERAP2DPP4 | |
| SCHEMBL8599837 | 0.81 | KMT2A (0.45) | ALOX15TSHRANPEPDPP4DPP8 | |
| SCHEMBL1768567 | 0.77 | ALOX15 (0.43) | ALOX15TSHRANPEPERAP2EPHX1 | |
| SCHEMBL1768564 | 0.77 | ALOX15 (0.43) | ALOX15TSHRANPEPERAP2EPHX1 | |
| SCHEMBL7350548 | 0.73 | TDP1 (0.72) | ALOX15TSHRANPEPERAP2EPHX1 | |
| SCHEMBL10446115 | 0.73 | ALOX15 (0.54) | ALOX15TSHRANPEPERAP2DPP4 | |
| Hydrochloric Acid SCHEMBL27579080 | 0.72 | TDP1 (0.69) | ALOX15TSHRANPEPERAP2EPHX1 | |
| SCHEMBL14167229 | 0.72 | TDP1 (0.48) | TSHRDPP4DPP8DPP9KMT2A | |
| SCHEMBL3633232 | 0.72 | ALOX15 (0.47) | ALOX15TSHRANPEPERAP2DPP4 | |
| SCHEMBL8596548 | 0.71 | KMT2A (0.46) | ANPEPDPP4DPP8DPP9BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841257-B2 | Inhibitors of STAT3 and uses thereof | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-09-23 | — | — | US | disclosed |