Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.41 |
| ▸ | CNR2 | P34972 | 5/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16302131 | 0.80 | CNR1 (0.42) | CNR1CNR2ALPLCRBNCRHR1 | |
| SCHEMBL847231 | 0.79 | SLC6A9 (0.47) | CNR1CNR2 | |
| SCHEMBL848669 | 0.74 | SMN1; SMN2 (0.50) | CNR1CNR2HSD11B1 | |
| SCHEMBL13555069 | 0.73 | ALPL (0.40) | CNR1CNR2ALPLCRBN | |
| SCHEMBL13551796 | 0.72 | CNR1 (0.41) | CNR1CNR2ALPLCRBNHTR2A | |
| Hydrochloric Acid SCHEMBL850774 | 0.71 | CNR1 (0.41) | CNR1CNR2ALPLCRBNHTR2A | |
| SCHEMBL849148 | 0.70 | DPP4 (0.43) | CNR1CNR2 | |
| SCHEMBL848929 | 0.70 | KMT2A (0.44) | CNR1CNR2 | |
| SCHEMBL850091 | 0.69 | MEN1 (0.50) | HSD11B1 | |
| SCHEMBL16104718 | 0.69 | CNR1 (0.41) | CNR1CNR2ALPLHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433940-B1 | SPIROIMIDAZOLONE DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2014-09-24 | — | — | EP | disclosed |