Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10052378 | 0.94 | CYP3A4 (0.43) | CYP3A4MMP2MMP9MCL1 | |
| SCHEMBL10060996 | 0.94 | CYP3A4 (0.43) | CYP3A4MMP2MMP9MCL1 | |
| SCHEMBL16508713 | 0.94 | CYP3A4 (0.43) | CYP3A4MMP2MMP9MCL1 | |
| SCHEMBL6877935 | 0.94 | CYP3A4 (0.43) | CYP3A4MMP2MMP9MCL1 | |
| SCHEMBL17704201 | 0.93 | CYP3A4 (0.42) | CYP3A4MMP2MMP9MCL1 | |
| SCHEMBL21486298 | 0.93 | CYP3A4 (0.42) | CYP3A4MMP2MMP9MCL1 | |
| SCHEMBL21508933 | 0.88 | MMP2 (0.34) | CYP3A4MMP2MMP9MCL1 | |
| SCHEMBL16106784 | 0.87 | MMP2 (0.34) | CYP3A4MMP2MMP9MCL1 | |
| SCHEMBL14159063 | 0.86 | CTSB (0.41) | — | |
| SCHEMBL8293449 | 0.86 | CTSB (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140296136-A1 | HCV NS3 PROTEASE INHIBITORS | MERCK SHARP & DOHME LLC | 2014-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296136-A1 | HCV NS3 PROTEASE INHIBITORS | HAVCR2, GTF3C3, CTSC | CYP3A4 154/4885MMP2 165/4885MMP9 445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.