Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 11/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16110343 | 1.00 | SLC7A5 (0.42) | SLC7A5ALOX15KDM1AMAOBMAOA | |
| SCHEMBL9886406 | 1.00 | SLC7A5 (0.42) | SLC7A5ALOX15KDM1AMAOBMAOA | |
| SCHEMBL29162265 | 0.83 | KDM1A (0.53) | SLC7A5KDM1AMAOBMAOA | |
| SCHEMBL9103100 | 0.80 | KMO (0.51) | KDM1AMAOBMAOA | |
| SCHEMBL13026715 | 0.76 | PARP1 (0.59) | SLC7A5ALOX15KDM1AMAOBSTAT3 | |
| SCHEMBL110296 | 0.75 | SLC7A5 (0.58) | SLC7A5ALOX15STAT3GABRA1GABRG2 | |
| Water SCHEMBL28897664 | 0.74 | SLC7A5 (0.56) | SLC7A5ALOX15STAT3GABRA1GABRG2 | |
| Hydrogen Peroxide SCHEMBL27146001 | 0.74 | SLC7A5 (0.60) | SLC7A5ALOX15STAT3GABRA1GABRG2 | |
| SCHEMBL28350987 | 0.74 | SLC7A5 (0.56) | SLC7A5ALOX15STAT3GABRA1GABRG2 | |
| SCHEMBL24890704 | 0.74 | DGAT2 (0.44) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9108990-B2 | Cyclopropyl MIDA boronate | RIGEL PHARMACEUTICALS, INC. (US) | 2015-08-18 | — | — | US | disclosed |
| US-20140296557-A1 | Cyclopropyl MIDA Boronate | MIDCAP FINANCIAL TRUST | 2014-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140296557-A1 | Cyclopropyl MIDA Boronate | MB, MMAB, MDK | SLC7A5 1318/4885ALOX15 3848/4885KDM1A 1354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.