SCHEMBL1611036

SCHEMBL1611036

Cc1ccc2c(c1)Cc1ccc(C)cc1C2=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 3/20 0.65
ELANE P08246 1/20 0.53
MAOA P21397 4/20 0.50
MAOB P27338 3/20 0.50
ACHE P22303 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA4 P22748 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
ALDH1A1 P00352 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
PARP10 Q53GL7 2/20 0.44
PARP11 Q9NR21 1/20 0.44
PARP1 P09874 1/20 0.44
MAPT P10636 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
LCK P06239 1/20 0.41
KDM4E B2RXH2 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11891506 0.94 METAP1 (0.71) METAP1ELANEMAOAMAOBACHE
SCHEMBL31124706 0.94 METAP1 (0.71) METAP1ELANEMAOAMAOBACHE
SCHEMBL1609651 0.94 METAP1 (0.71) METAP1ELANEMAOAMAOBACHE
SCHEMBL6056920 0.92 METAP1 (0.69) METAP1ELANEMAOAMAOBACHE
SCHEMBL6056983 0.90 METAP1 (0.67) METAP1ELANEMAOAMAOBACHE
SCHEMBL6905059 0.89 MAOA (0.67) METAP1ELANEMAOAMAOBACHE
SCHEMBL6905673 0.89 MAOA (0.67) METAP1ELANEMAOAALDH1A1SMN1; SMN2
SCHEMBL17899376 0.88 MAOA (0.58) METAP1ELANEMAOAMAOBLCK
SCHEMBL17899377 0.88 METAP1 (0.56) METAP1ELANEMAOAMAOBACHE
SCHEMBL21694418 0.83 METAP1 (0.52) METAP1ELANEMAOAMAOBACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180079962-A1 LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF MAGNOLIA PURPLE CORPORATION (JP) 2018-03-22 US disclosed
US-9868907-B2 Liquid crystal display device and manufacturing method thereof JAPAN DISPLAY INC. (JP) 2018-01-16 US disclosed
US-9718692-B2 Method for exfoliating carbonaceous materials containing graphite, assisted by a Diels-Alder reaction UNIVERSITÉ DE BORDEAUX (FR) 2017-08-01 US disclosed
US-20160194207-A1 METHOD FOR EXFOLIATING CARBONACEAOUS MATERIALS CONTAINING GRAPHITE, ASSISTED BY A DIELS-ALDER REACTION INSTITUT POLYTECHNIQUE DE BORDEAUX (FR) 2016-07-07 US disclosed
US-20150210923-A1 LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF MAGNOLIA PURPLE CORPORATION (JP) 2015-07-30 US disclosed
US-9090819-B2 Organic electroluminescent element, display device, illuminating device and condensed polycyclic heterocyclic compound Konica Minolta, Inc. (JP) 2015-07-28 US disclosed
US-9090819-B2 Organic electroluminescent element, display device, illuminating device and condensed polycyclic heterocyclic compound Konica Minolta, Inc. (JP) 2015-07-28 US disclosed
US-9028926-B2 Liquid crystal display device and manufacturing method thereof JAPAN DISPLAY INC. (JP) 2015-05-12 US disclosed
US-20140046004-A1 LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF JAPAN DISPLAY, INC. (JP) 2014-02-13 US disclosed
US-20120085997-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, ILLUMINATING DEVICE AND CONDENSED POLYCYCLIC HETEROCYCLIC COMPOUND KONICA MINOLTA HOLDINGS, INC. (JP) 2012-04-12 US disclosed
US-20120085997-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, ILLUMINATING DEVICE AND CONDENSED POLYCYCLIC HETEROCYCLIC COMPOUND KONICA MINOLTA HOLDINGS, INC. (JP) 2012-04-12 US disclosed
US-20090053430-A1 Liquid Crystal Display Device and Manufacturing Method Thereof HITACHI DISPLAYS. LTD. 2009-02-26 US disclosed
US-6815481-B2 FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-09 US disclosed
US-20020032256-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120085997-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, ILLUMINATING DEVICE AND CONDENSED POLYCYCLIC HETEROCYCLIC COMPOUND CCNE2, C1S, SCO2 METAP1 2747/4885ELANE 1052/4885MAOA 824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.