Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 9/20 | 0.58 |
| ▸ | MAOB | P27338 | 9/20 | 0.58 |
| ▸ | METAP1 | P53582 | 2/20 | 0.56 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1611036 | 0.88 | METAP1 (0.65) | MAOAMAOBMETAP1LCKELANE | |
| SCHEMBL8756228 | 0.88 | MAOA (0.59) | MAOAMAOBHSD17B1CYP19A1ESR1 | |
| SCHEMBL8771857 | 0.86 | HSD17B1 (0.54) | MAOAMAOBMETAP1MIFHSD17B1 | |
| SCHEMBL1609651 | 0.86 | METAP1 (0.71) | MAOAMAOBMETAP1LCKELANE | |
| SCHEMBL6056920 | 0.84 | METAP1 (0.69) | MAOAMAOBMETAP1LCKELANE | |
| SCHEMBL12704854 | 0.82 | ESR1 (0.47) | MAOAMAOBMETAP1HSD17B1ESR1 | |
| SCHEMBL15869784 | 0.82 | HSD17B1 (0.58) | MAOAMAOBMETAP1MIFHSD17B1 | |
| SCHEMBL6056983 | 0.82 | METAP1 (0.67) | MAOAMAOBMETAP1LCKELANE | |
| SCHEMBL31124706 | 0.82 | METAP1 (0.71) | MAOAMAOBMETAP1ELANE | |
| SCHEMBL11891506 | 0.82 | METAP1 (0.71) | MAOAMAOBMETAP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9718692-B2 | Method for exfoliating carbonaceous materials containing graphite, assisted by a Diels-Alder reaction | UNIVERSITÉ DE BORDEAUX (FR) | 2017-08-01 | — | — | US | disclosed |
| US-20160194207-A1 | METHOD FOR EXFOLIATING CARBONACEAOUS MATERIALS CONTAINING GRAPHITE, ASSISTED BY A DIELS-ALDER REACTION | INSTITUT POLYTECHNIQUE DE BORDEAUX (FR) | 2016-07-07 | — | — | US | disclosed |