Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 12/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16111262 | 0.85 | LMNA (0.50) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL16112217 | 0.83 | MAPT (0.47) | LMNAALDH1A1MAPT | |
| SCHEMBL16839640 | 0.82 | SMN1; SMN2 (0.44) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL18440208 | 0.80 | MEN1 (0.65) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL16112134 | 0.80 | MMP13 (0.48) | MAPT | |
| SCHEMBL12346133 | 0.79 | MEN1 (0.59) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1919601 | 0.77 | MEN1 (0.61) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL20730254 | 0.76 | LMNA (0.56) | LMNAMEN1KMT2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL1476096 | 0.76 | MEN1 (0.60) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL24241978 | 0.74 | MEN1 (0.47) | LMNAMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014160649-A1 | HYDROXAMIC ACID DERIVATIVES AS LPXC INHIBITORS FOR THE TREATMENT OF BACTERIAL INFECTIONS | NOVARTIS AG (CH) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014160649-A1 | HYDROXAMIC ACID DERIVATIVES AS LPXC INHIBITORS FOR THE TREATMENT OF BACTERIAL INFECTIONS | NOVARTIS AG (CH) | 2014-10-02 | — | — | WO | disclosed |