Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL971336 | 0.88 | LMNA (0.40) | LMNANPSR1 | |
| Hydrochloric Acid SCHEMBL3928099 | 0.86 | LMNA (0.39) | LMNANPSR1 | |
| SCHEMBL2086600 | 0.83 | — | — | |
| SCHEMBL231396 | 0.80 | — | — | |
| SCHEMBL2788173 | 0.79 | ALOX15 (0.34) | LMNA | |
| Bromide SCHEMBL21798034 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL233616 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL27585730 | 0.78 | NPSR1 (0.41) | LMNANPSR1NSD2 | |
| SCHEMBL29954216 | 0.74 | — | — | |
| SCHEMBL29955171 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014160649-A1 | HYDROXAMIC ACID DERIVATIVES AS LPXC INHIBITORS FOR THE TREATMENT OF BACTERIAL INFECTIONS | NOVARTIS AG (CH) | 2014-10-02 | — | — | WO | disclosed |