Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.54 |
| ▸ | ALPL | P05186 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16111837 | 0.85 | ALPL (0.60) | HPGDSALPLMAPTTP53CASP3 | |
| SCHEMBL25126406 | 0.81 | PLA2G10 (0.48) | ALPLMAPTTP53KMT2AGAA | |
| SCHEMBL25409779 | 0.80 | ALPL (0.57) | HPGDSALPLMAPTTP53CASP3 | |
| SCHEMBL16112173 | 0.80 | HPGDS (0.59) | HPGDSALPLMAPTTP53CASP3 | |
| SCHEMBL595997 | 0.79 | ALPL (0.75) | HPGDSALPLMAPTTP53CASP3 | |
| SCHEMBL18187534 | 0.79 | MAPT (0.62) | HPGDSALPLMAPTTP53CASP3 | |
| SCHEMBL31461711 | 0.76 | MAPT (0.67) | HPGDSALPLMAPTTP53CASP3 | |
| SCHEMBL7911349 | 0.76 | HPGDS (0.53) | HPGDSALPLMAPTTP53CASP3 | |
| SCHEMBL16730821 | 0.75 | MAPT (0.69) | HPGDSALPLMAPTTP53CASP3 | |
| SCHEMBL13710322 | 0.75 | MAPT (0.69) | HPGDSALPLMAPTTP53CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014159214-A1 | HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | CHDI FOUNDATION, INC. (US) | 2014-10-02 | — | — | WO | disclosed |