Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.68 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.68 |
| ▸ | CSK | P41240 | 1/20 | 0.68 |
| ▸ | CAMK1G | Q96NX5 | 1/20 | 0.68 |
| ▸ | FLT3 | P36888 | 3/20 | 0.56 |
| ▸ | CCR4 | P51679 | 2/20 | 0.56 |
| ▸ | MELK | Q14680 | 4/20 | 0.54 |
| ▸ | LYN | P07948 | 1/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.54 |
| ▸ | FER | P16591 | 1/20 | 0.54 |
| ▸ | MATK | P42679 | 1/20 | 0.54 |
| ▸ | BLK | P51451 | 1/20 | 0.54 |
| ▸ | BMX | P51813 | 1/20 | 0.54 |
| ▸ | TEK | Q02763 | 1/20 | 0.54 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.54 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.54 |
| ▸ | CAMK1 | Q14012 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1612950 | 0.92 | BTK (0.76) | BTKERBB4CSKCAMK1GFLT3 | |
| SCHEMBL1612951 | 0.92 | BTK (0.76) | BTKERBB4CSKCAMK1GFLT3 | |
| Aminoquinol SCHEMBL706642 | 0.81 | HSD17B10 (0.62) | BTKERBB4CSKCAMK1GHSD17B10 | |
| Aminoquinol SCHEMBL29578527 | 0.81 | HSD17B10 (0.62) | BTKERBB4CSKCAMK1GHSD17B10 | |
| Aminoquinol SCHEMBL706641 | 0.81 | HSD17B10 (0.62) | BTKERBB4CSKCAMK1GHSD17B10 | |
| SCHEMBL3542142 | 0.80 | CCR4 (0.72) | BTKERBB4CSKCAMK1GFLT3 | |
| SCHEMBL3542141 | 0.80 | CCR4 (0.72) | BTKERBB4CSKCAMK1GFLT3 | |
| SCHEMBL3541032 | 0.80 | CCR4 (0.71) | BTKERBB4CSKCAMK1GFLT3 | |
| SCHEMBL3541029 | 0.80 | CCR4 (0.71) | BTKERBB4CSKCAMK1GFLT3 | |
| SCHEMBL7619465 | 0.79 | BTK (0.71) | BTKERBB4CSKCAMK1GFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160058749-A1 | TREATMENTS FOR NEUROPATHY | CHILDRENS MEDICAL CENTER (US) | 2016-03-03 | — | — | US | disclosed |
| US-20160045487-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROPATHY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-02-18 | — | — | US | disclosed |
| US-20110086878-A1 | Treatments for Neuropathy | NIH-DEITR | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160058749-A1 | TREATMENTS FOR NEUROPATHY | NGF, BDNF, NTRK2 | BTK 4200/4885ERBB4 1119/4885CSK 3142/4885 |
| US-20160045487-A1 | COMPOSITIONS AND METHODS FOR TREATING NEUROPATHY | PMP22, GAP43, NGF | BTK 3547/4885ERBB4 1537/4885CSK 4098/4885 |
| US-20110086878-A1 | Treatments for Neuropathy | NGF, BDNF, NTRK2 | BTK 4200/4885ERBB4 1119/4885CSK 3142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.