Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.66 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.66 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.56 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.47 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.47 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27490732 | 0.89 | PTGS1 (0.72) | PTGS1GSTK1FOLH1NAALAD2RIMKLA | |
| SCHEMBL29559136 | 0.89 | PTGS1 (0.72) | PTGS1GSTK1FOLH1NAALAD2RIMKLA | |
| SCHEMBL28502763 | 0.86 | PTGS1 (0.69) | PTGS1GSTK1FOLH1NAALAD2RIMKLA | |
| SCHEMBL2928611 | 0.85 | PTGS1 (0.67) | PTGS1GSTK1FOLH1GLO1NOD1 | |
| SCHEMBL236405 | 0.85 | PTGS1 (0.67) | PTGS1GSTK1FOLH1NAALAD2RIMKLA | |
| SCHEMBL6665444 | 0.85 | PTGS1 (0.67) | PTGS1GSTK1FOLH1NAALAD2RIMKLA | |
| SCHEMBL20787756 | 0.85 | PTGS1 (0.67) | PTGS1GSTK1FOLH1GLO1NOD1 | |
| SCHEMBL17629937 | 0.85 | PTGS1 (0.67) | PTGS1GSTK1FOLH1NAALAD2RIMKLA | |
| SCHEMBL20787749 | 0.85 | PTGS1 (0.67) | PTGS1GSTK1FOLH1NAALAD2RIMKLA | |
| SCHEMBL1646531 | 0.85 | PTGS1 (0.71) | PTGS1GSTK1FOLH1NAALAD2RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014159720-A1 | METHODS AND COMPOSITIONS FOR INHIBITING GLYOXALASE 1 (GLO1) | THE UNIVERSITY OF CHICAGO (US) | 2014-10-02 | — | — | WO | disclosed |