SCHEMBL236405

SCHEMBL236405

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nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.67
GSTK1 Q9Y2Q3 1/20 0.67
MAPT P10636 2/20 0.53
PTGS2 P35354 2/20 0.53
KDM4E B2RXH2 1/20 0.53
THRB P10828 1/20 0.53
ALOX15 P16050 1/20 0.53
NFKB1 P19838 1/20 0.53
THPO P40225 1/20 0.53
RECQL P46063 1/20 0.53
BLM P54132 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
GLO1 Q04760 2/20 0.50
FOLH1 Q04609 3/20 0.47
NOD1 Q9Y239 3/20 0.43
FNTA P49354 2/20 0.40
FNTB P49356 2/20 0.40
PGGT1B P53609 1/20 0.40
GNPAT O15228 2/20 0.39
ACE P12821 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20787749 1.00 PTGS1 (0.67) PTGS1GSTK1MAPTPTGS2KDM4E
SCHEMBL20787756 0.89 PTGS1 (0.67) PTGS1GSTK1GLO1FOLH1NOD1
SCHEMBL6665444 0.89 PTGS1 (0.67) PTGS1GSTK1MAPTPTGS2GLO1
SCHEMBL2928611 0.89 PTGS1 (0.67) PTGS1GSTK1GLO1FOLH1NOD1
Glutathione SCHEMBL237150 0.89 PTGS1 (0.83) PTGS1GSTK1MAPTPTGS2KDM4E
Glutathione SCHEMBL5131162 0.89 PTGS1 (0.83) PTGS1GSTK1MAPTPTGS2KDM4E
Glutathione SCHEMBL237151 0.89 PTGS1 (0.83) PTGS1GSTK1MAPTPTGS2KDM4E
Glutathione SCHEMBL19612768 0.89 PTGS1 (0.83) PTGS1GSTK1MAPTPTGS2KDM4E
SCHEMBL28502763 0.88 PTGS1 (0.69) PTGS1GSTK1MAPTPTGS2KDM4E
SCHEMBL23161509 0.88 PTGS1 (0.69) PTGS1GSTK1MAPTPTGS2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119350436-A Method for synthesizing acetyl glutathione by biological enzyme method 上海克琴科技有限公司 2025-01-24 CN claimed
EP-3270889-B1 TARGETED LIPOSOMAL DELIVERY OF CGMP ANALOGUES MIRECA MEDICINES GMBH (DE) 2024-02-07 EP claimed
US-11547757-B2 Elimination of exotic pathogens Healing Oil Extracts, LLC. (US) 2023-01-10 US claimed
WO-2022074181-A1 NANOCARRIER FORMULATIONS FOR INHALATION EnhanX Biopharm Inc. (TW) 2022-04-14 WO claimed
EP-3395372-B1 GLUTATHIONE-BASED DRUG DELIVERY SYSTEM ENHANX BIOPHARM INC (TW) 2022-04-06 EP claimed
EP-1240902-B1 CARBONYL STRESS-AMELIORATING AGENTS KUROKAWA KIYOSHI (JP) 2013-02-13 EP claimed
US-20110245188-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY DISEASES OR CONDITIONS MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) 2011-10-06 US claimed
US-20110160305-A1 Oral Delivery of Therapeutic Doses of Glutathione AGB INNOVATIONS, LLC 2011-06-30 US claimed
US-20100247463-A1 N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE YU RUEY J 2010-09-30 US claimed
US-7776844-B2 N-(phosphonoalkyl)-amino acids, derivatives thereof and compositions and methods of use YU RUEY J 2010-08-17 US claimed
WO-2004012652-A9 TREATMENT OF MULTIPLE SCLEROSIS WITH BRAIN TARGETED ANTI OXIDANT COMPOUNDS YISSUM RES DEV CO (IL) 2004-06-17 WO claimed
WO-2004012652-A2 TREATMENT OF MULTIPLE SCLEROSIS WITH BRAIN TARGETED ANTI OXIDANT COMPOUNDS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2004-02-12 WO claimed
WO-2004010968-A1 NON-AMPHOTERIC GLUTATHIONE DERIVATIVE COMPOSITIONS FOR TOPICAL APPLICATION YU RUEY J (US) 2004-02-05 WO claimed
EP-1242070-A4 TREATMENT OF ISCHEMIC BRAIN INJURIES WITH BRAIN TARGETTED ANTIOXIDANT COMPOUNDS YISSUM RES DEV CO (IL) 2003-05-28 EP claimed
US-20030083266-A1 Treatment of ischemic brain injuries with brain targeted antioxidant compounds RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2003-05-01 US claimed
EP-1242070-A2 TREATMENT OF ISCHEMIC BRAIN INJURIES WITH BRAIN TARGETTED ANTIOXIDANT COMPOUNDS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2002-09-25 EP claimed
US-6369106-B1 SULFHYDRYL CONTAINING COMPOUND AS ANTIOXIDANT YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2002-04-09 US claimed
WO-2001047469-A2 TREATMENT OF ISCHEMIC BRAIN INJURIES WITH BRAIN TARGETTED ANTIOXIDANT COMPOUNDS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2001-07-05 WO claimed
EP-0948258-A1 BRAIN TARGETED LOW MOLECULAR WEIGHT HYDROPHOBIC ANTIOXIDANT COMPOUNDS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 1999-10-13 EP claimed
WO-1998029375-A1 BRAIN TARGETED LOW MOLECULAR WEIGHT HYDROPHOBIC ANTIOXIDANT COMPOUNDS YISSUM RESEARCH AND DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 1998-07-09 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110245188-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF INFLAMMATORY DISEASES OR CONDITIONS HMGCR, GCKR, GSR PTGS1 173/4885GSTK1 15/4885MAPT 2508/4885
US-20030083266-A1 Treatment of ischemic brain injuries with brain targeted antioxidant compounds GPX4, GPX1, TXN2 PTGS1 192/4885GSTK1 13/4885MAPT 1162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.