SCHEMBL16115100

SCHEMBL16115100

C=C(C)C(=O)OC(CC)[Si](OCC)(OCC)OCC.C=C(C)C(=O)OC(CC)[Si](OCCC)(OCCC)OCCC

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.37
TSHR P16473 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL193617 0.95 TSHR (0.39) THRBTSHR
SCHEMBL25276153 0.92 THRB (0.38) THRBTSHR
SCHEMBL138292 0.92 THRB (0.38) THRBTSHR
Hydrogen Sulfide SCHEMBL4951624 0.91 THRB (0.37) THRBTSHR
Methyl Alcohol SCHEMBL28830048 0.91 THRB (0.37) THRBTSHR
SCHEMBL29927929 0.90 THRB (0.36) THRBTSHR
Alcohol SCHEMBL28598934 0.89 THRB (0.36) THRBTSHR
SCHEMBL11464441 0.86 ALDH1A1 (0.34) THRBTSHR
SCHEMBL141271 0.86 TSHR (0.44) THRBTSHR
SCHEMBL3903524 0.85 TSHR (0.50) THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2970539-A1 HYBRID LATEX PARTICLES FOR SELF-STRATIFYING COATINGS The Sherwin-Williams Company (US) 2016-01-20 EP claimed
US-9000069-B1 Self-stratifying coatings THE SHERWIN-WILLIAMS COMPANY (US) 2015-04-07 US claimed
US-20140303281-A1 HYBRID LATEX PARTICLES FOR SELF-STRATIFYING COATINGS THE SHERWIN-WILLIAMS COMPANY (US) 2014-10-09 US claimed
WO-2014159162-A1 HYBRID LATEX PARTICLES FOR SELF-STRATIFYING COATINGS THE SHERWIN-WILLIAMS COMPANY (US) 2014-10-02 WO claimed
US-9000069-B1 Self-stratifying coatings THE SHERWIN-WILLIAMS COMPANY (US) 2015-04-07 US disclosed