Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TOP1 | P11387 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16114813 | 0.89 | TSHR (0.55) | TSHRKDM4EALDH1A1GAARAB9A | |
| SCHEMBL30362191 | 0.86 | PPARG (0.55) | TSHRGAARAB9APKMPPARG | |
| SCHEMBL3982009 | 0.86 | PPARG (0.55) | TSHRGAARAB9APKMPPARG | |
| SCHEMBL3256083 | 0.83 | NPC1 (0.54) | KDM4EALDH1A1MAPTMAPK1MEN1 | |
| SCHEMBL13345457 | 0.81 | PPARG (0.40) | ALDH1A1GAAPPARGPPARANR1H4 | |
| SCHEMBL566467 | 0.81 | CREBBP (0.60) | ALDH1A1GAAMAPTCREBBPMEN1 | |
| SCHEMBL2283371 | 0.80 | PPARG (0.51) | KDM4EALDH1A1GAARAB9APPARG | |
| SCHEMBL9865843 | 0.80 | KDM5A (0.50) | KDM4EALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL30779358 | 0.80 | MAPT (0.46) | KDM4EALDH1A1GAARAB9APKM | |
| SCHEMBL2890796 | 0.80 | MAPT (0.46) | KDM4EALDH1A1GAARAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160032047-A1 | Peg-based adhesive phenylic derivatives and methods of synthesis and use | DSM IP ASSETS B.V. (NL) | 2016-02-04 | — | — | US | disclosed |
| EP-2968667-A1 | PEG-BASED ADHESIVE PHENYLIC DERIVATIVES AND METHODS OF SYNTHESIS AND USE | DSM IP Assets B.V. (NL) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014158288-A1 | PEG-BASED ADHESIVE PHENYLIC DERIVATIVES AND METHODS OF SYNTHESIS AND USE | DSM IP ASSETS B.V. (NL) | 2014-10-02 | — | — | WO | disclosed |