Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | LTB4R | Q15722 | 6/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | TPMT | P51580 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3982009 | 1.00 | PPARG (0.55) | PPARGPPARANR1H4MAPK1GAA | |
| SCHEMBL113522 | 0.89 | CA12 (0.53) | MAPK1CA12CA1CA2CA4 | |
| SCHEMBL3601292 | 0.89 | KDM4E (0.52) | GAAMEN1POLBKMT2AHDAC1 | |
| SCHEMBL16115115 | 0.86 | TSHR (0.55) | PPARGPPARANR1H4MAPK1GAA | |
| SCHEMBL3256083 | 0.85 | NPC1 (0.54) | MAPK1MEN1POLBKMT2A | |
| SCHEMBL3982928 | 0.85 | HDAC1 (0.49) | PPARGPPARANR1H4MAPK1GAA | |
| SCHEMBL20053747 | 0.84 | LTB4R (0.61) | PPARGPPARANR1H4MAPK1GAA | |
| SCHEMBL566467 | 0.83 | CREBBP (0.60) | GAALTB4RMEN1POLBKMT2A | |
| SCHEMBL13345457 | 0.83 | PPARG (0.40) | PPARGPPARANR1H4MAPK1GAA | |
| SCHEMBL2283371 | 0.82 | PPARG (0.51) | PPARGMAPK1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110698459-B | 1-phenyl-2-pyridylalkyl alcohol derivatives as phosphodiesterase inhibitors | 奇斯药制品公司 | 2023-05-05 | — | — | CN | disclosed |