Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18725149 | 0.82 | MAOB (0.37) | BRD4PTGER1ALDH1A1LMNAMAPT | |
| SCHEMBL18725150 | 0.82 | MAOB (0.37) | BRD4PTGER1ALDH1A1LMNAMAPT | |
| SCHEMBL16137772 | 0.78 | BRD4 (0.37) | BRD4PTGER1ALDH1A1KDM4ELMNA | |
| SCHEMBL16108509 | 0.77 | LMNA (0.50) | PTGER1ALDH1A1LMNAMAPTTRPV3 | |
| SCHEMBL8623878 | 0.76 | PTGER1 (0.62) | PTGER1ALDH1A1KDM4ETRPV3 | |
| SCHEMBL16109000 | 0.75 | PTGER1 (0.42) | PTGER1ALDH1A1GRM5TRPV3 | |
| SCHEMBL5755997 | 0.74 | KCNH2 (0.52) | PTGER1ALDH1A1GRM5TRPV3 | |
| SCHEMBL15898833 | 0.74 | PTGER1 (0.53) | PTGER1ALDH1A1GRM5TRPV3 | |
| SCHEMBL1172003 | 0.73 | MRGPRX4 (0.54) | ALDH1A1KDM4E | |
| SCHEMBL28406351 | 0.73 | PTGER1 (0.45) | PTGER1ALDH1A1GRM5TRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2978754-B1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-10 | — | — | EP | disclosed |
| EP-2978754-B1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-10 | — | — | EP | disclosed |
| EP-2978747-B1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-04-19 | — | — | EP | disclosed |
| EP-2978747-B1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-04-19 | — | — | EP | disclosed |
| EP-2978747-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2016-02-03 | — | — | EP | disclosed |
| EP-2978754-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2016-02-03 | — | — | EP | disclosed |
| WO-2014154726-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014154726-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014154727-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014154727-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-10-02 | — | — | WO | disclosed |