Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18725149 | 0.88 | MAOB (0.37) | BRD4MAOBALDH1A1PTGER1MEN1 | |
| SCHEMBL18725150 | 0.88 | MAOB (0.37) | BRD4MAOBALDH1A1PTGER1MEN1 | |
| SCHEMBL16115402 | 0.78 | BRD4 (0.43) | BRD4TRPV3ALDH1A1PTGER1MAPT | |
| SCHEMBL16137781 | 0.76 | BRD4 (0.38) | BRD4MAOBALDH1A1MEN1HSP90AA1 | |
| SCHEMBL23834794 | 0.68 | ALDH1A1 (0.47) | TRPV3MAOBALDH1A1PTGER1MEN1 | |
| SCHEMBL29921094 | 0.68 | ALDH1A1 (0.47) | TRPV3MAOBALDH1A1PTGER1MEN1 | |
| SCHEMBL16134440 | 0.67 | MMP13 (0.37) | TRPV3ALDH1A1PTGER1MEN1HSP90AA1 | |
| SCHEMBL16108509 | 0.65 | LMNA (0.50) | TRPV3ALDH1A1PTGER1MAPTPKM | |
| SCHEMBL16137688 | 0.65 | KMT2A (0.40) | BRD4MAOBALDH1A1PTGER1MEN1 | |
| SCHEMBL16114824 | 0.65 | MRGPRX4 (0.40) | BRD4MAOBALDH1A1MEN1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014154727-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014154726-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-10-02 | — | — | WO | disclosed |