Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16137689 | 0.87 | KMT2A (0.47) | MRGPRX4MEN1KMT2ABRD4MAOB | |
| SCHEMBL16114823 | 0.83 | MRGPRX4 (0.40) | MRGPRX4MEN1KMT2ABRD4MAOB | |
| SCHEMBL16114824 | 0.83 | MRGPRX4 (0.40) | MRGPRX4MEN1KMT2ABRD4MAOB | |
| SCHEMBL1172003 | 0.79 | MRGPRX4 (0.54) | MRGPRX4MAOBNR4A2SRD5A2KDM4E | |
| SCHEMBL16137781 | 0.79 | BRD4 (0.38) | MRGPRX4MEN1KMT2ABRD4MAOB | |
| SCHEMBL7420476 | 0.77 | LMNA (0.62) | MRGPRX4MEN1KMT2AMAOBNR4A2 | |
| SCHEMBL7428565 | 0.76 | MEN1 (0.79) | MRGPRX4MEN1KMT2AMAOBNR4A2 | |
| SCHEMBL16137683 | 0.75 | MEN1 (0.62) | MRGPRX4MEN1KMT2AMAOBNR4A2 | |
| SCHEMBL14018084 | 0.74 | PARP10 (0.63) | MRGPRX4MEN1KMT2AMAOBNR4A2 | |
| SCHEMBL13590516 | 0.74 | PLA2G4B (0.49) | MEN1KMT2ABRD4MAOBNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2978754-B1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-10 | — | — | EP | disclosed |
| EP-2978754-B1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-10 | — | — | EP | disclosed |
| EP-2978747-B1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-04-19 | — | — | EP | disclosed |
| EP-2978747-B1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-04-19 | — | — | EP | disclosed |
| EP-2978747-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2016-02-03 | — | — | EP | disclosed |
| EP-2978754-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2016-02-03 | — | — | EP | disclosed |
| WO-2014154727-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014154727-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014154726-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014154726-A1 | BIARYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2014-10-02 | — | — | WO | disclosed |